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GenSeq is a subscription-based database of "genetic sequences from worldwide patents, manually annotated to highlight IP context and biological significance" created by Thomson Reuters.[1] The database covers "all biological sequences patented since 1981 from 41 worldwide patent-issuing authorities, including WO, US, EP, JP, DE, IN and CN" and contains over 27 million biological sequences from over 150,000 patent documents.[1] About 600 patents are added every two weeks to the database.[1]


The biological sequence information in the database includes:[2]

  • Nucleic acid sequences 10 or more bases in length.
  • Amino acid sequences 4 or more residues in length.
  • All PCR primers and probes of any length.
  • Sequence and contextual information, irrespective of its location within a patent, including organism name, gene/protein name, sequence modifications, associated disease information.
  • Links to identical records from NCBI, SWISSPROT, Gene Ontology (GO) annotation, and sequence aliases.

Each indexed record in the database contains:[2]

  • Enhanced patent titles.
  • English language abstract from non-English sources.
  • Sequence location within the patent document.
  • Original source organism.
  • Highlighted biologically significant regions of the sequence.
  • Standardized, full bibliographic data.
  • Commentary clarifying sequence novelty and utility underlying each invention.


According to the Thomson Reuters website, users can access GenSeq through the following platforms:[3]

  • An EMBL-like FTP-delivered flat file, delivered every two weeks for inclusion in your in-house information system.
  • Companion database GENESEQ™ FASTAlert that enables searching of new sequences.
  • GenomeQuest
  • STN International
  • Thomson Pharma ®

According to the SequenceBase website[4], user can access GENESEQ™ and FASTAlert via the SequenceBase BLAST Search Portal

Current GENESEQ™ coverage:


  1. 1.0 1.1 1.2 "GenSqeq Overview." Thomson Reuters website, Accessed September 15, 2011.
  2. 2.0 2.1 "GenSeq What's Included." Thomson Reuters website, Accessed September 15, 2011.
  3. "GenSeq Access Options." Thomson Reuters website, Accessed September 15, 2011.
  4. Thomson Reuters GENESEQ™ and GENESEQ™ FASTAlert now available via the SequenceBase BLAST Search Portal,

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